| Date | Rencontre | Comp. | Fiche | ||
| 18 juil. | AmaZulu FC | 0-1 | Manchester United | AMC | |
| 21 juil. | Ajax Cape Town | 1-1 | Manchester United | AMC | |
| 25 juil. | Shanghai Shenhua | 0-1 | Manchester United | AMC | |
| 5 août | Valerenga | 0-0 | Manchester United | AMC | |
| 8 août | FC Barcelone | 02-00 | Manchester United | AMC | |
| 11 août | Hannover 96 | 3-4 | Manchester United | AMC | |
| 20 août | Everton FC | 1-0 | Manchester United | EPL EPL1 |  |
| 25 août | Manchester United | 3-2 | Fulham FC | EPL EPL2 | |
| 2 sept. | Southampton FC | 2-3 | Manchester United | EPL EPL3 | |
| 15 sept. | Manchester United | 4-0 | Wigan Athletic | EPL EPL4 | |
| 19 sept. | Manchester United | 1-0 | Galatasaray | C1 1 | |
| 23 sept. | Liverpool FC | 1-2 | Manchester United | EPL EPL5 | |
| 26 sept. | Manchester United | 2-1 | Newcastle United | CC 3 | |
| 29 sept. | Manchester United | 2-3 | Tottenham Hotspur | EPL EPL6 | |
| 2 oct. | CFR Cluj | 1-2 | Manchester United | C1 1 | |
| 7 oct. | Newcastle United | 0-3 | Manchester United | EPL EPL7 | |
| 20 oct. | Manchester United | 4-2 | Stoke City | EPL EPL8 | |
| 23 oct. | Manchester United | 3-2 | Sporting Braga | C1 1 | |
| 28 oct. | Chelsea FC | 2-3 | Manchester United | EPL EPL9 | |
| 31 oct. | Chelsea FC | 5-4 | Manchester United | CC 4 | |
| 3 nov. | Manchester United | 2-1 | Arsenal FC | EPL EPL10 | |
| 7 nov. | Sporting Braga | 1-3 | Manchester United | C1 1 | |
| 10 nov. | Aston Villa | 2-3 | Manchester United | EPL EPL11 | |
| 17 nov. | Norwich City | 1-0 | Manchester United | EPL EPL12 | |
| 20 nov. | Galatasaray | 1-0 | Manchester United | C1 1 | |
| 24 nov. | Manchester United | 3-1 | Queens Park Rangers | EPL EPL13 | |
| 28 nov. | Manchester United | 1-0 | West Ham United | EPL EPL14 | |
| 1er déc. | Reading | 3-4 | Manchester United | EPL EPL15 | |
| 5 déc. | Manchester United | 0-1 | CFR Cluj | C1 1 | |
| 9 déc. | Manchester City | 2-3 | Manchester United | EPL EPL16 | |
| 15 déc. | Manchester United | 3-1 | Sunderland AFC | EPL EPL17 | |
| 23 déc. | Swansea | 1-1 | Manchester United | EPL EPL18 | |
| 26 déc. | Manchester United | 4-3 | Newcastle United | EPL EPL19 | |
| 29 déc. | Manchester United | 2-0 | West Bromwich | EPL EPL20 | |
| 1er janv. | Wigan Athletic | 0-4 | Manchester United | EPL EPL21 | |
| 5 janv. | West Ham United | 2-2 | Manchester United | CUP 3 | |
| 13 janv. | Manchester United | 2-1 | Liverpool FC | EPL EPL22 | |
| 16 janv. | Manchester United | 1-0 | West Ham United | CUP 3 | |
| 20 janv. | Tottenham Hotspur | 1-1 | Manchester United | EPL EPL23 | |
| 26 janv. | Manchester United | 4-1 | Fulham FC | CUP 1/16 | |
| 30 janv. | Manchester United | 2-1 | Southampton FC | EPL EPL24 | |
| 2 fév. | Fulham FC | 0-1 | Manchester United | EPL EPL25 | |
| 10 fév. | Manchester United | 2-0 | Everton FC | EPL EPL26 | |
| 13 fév. | Real Madrid | 1-1 | Manchester United | C1 1/8 | |
| 18 fév. | Manchester United | 2-1 | Reading | CUP 1/8 | |
| 23 fév. | Queens Park Rangers | 0-2 | Manchester United | EPL EPL27 | |
| 2 mars | Manchester United | 4-0 | Norwich City | EPL EPL28 | |
| 5 mars | Manchester United | 1-2 | Real Madrid | C1 1/8 | |
| 10 mars | Manchester United | 2-2 | Chelsea FC | CUP 1/4 | |
| 16 mars | Manchester United | 1-0 | Reading | EPL EPL30 | |
| 30 mars | Sunderland AFC | 0-1 | Manchester United | EPL EPL31 | |
| 1er avril | Chelsea FC | 1-0 | Manchester United | CUP 1/4 | |
| 8 avril | Manchester United | 1-2 | Manchester City | EPL EPL32 | |
| 14 avril | Stoke City | 0-2 | Manchester United | EPL EPL33 | |
| 17 avril | West Ham United | 2-2 | Manchester United | EPL EPL29 | |
| 22 avril | Manchester United | 3-0 | Aston Villa | EPL EPL34 | |
| 28 avril | Arsenal FC | 1-1 | Manchester United | EPL EPL35 | |
| 5 mai | Manchester United | 0-1 | Chelsea FC | EPL EPL36 | |
| 12 mai | Manchester United | 2-1 | Swansea | EPL EPL37 | |
| 19 mai | West Bromwich | 5-5 | Manchester United | EPL EPL38 | |
